In these talk we highlight the main results about dark matter (DM) search in dwarf irregular galaxies with the Fermi Large Area Telescope. We analyze 11 years of Fermi-LAT data corresponding to the sky regions of 7 dwarf irregular (dIrr) galaxies. DIrrs are DM dominated systems, recently proposed as interesting targets for the indirect search of DM with gamma-rays. We create a spatial template of the expected DM-induced gamma-ray signal with the CLUMPY code, to be used in the analysis of Fermi-LAT data. No significant emission is detected from any of the targets in our sample. Thus, we compute the upper limits on the DM annihilation cross-section versus mass parameter space. The strongest constraints are obtained for 𝑏𝑏 ̄ and are at the level of ⟨𝜎𝑣⟩ ∼ 7 × 10−26cm3s−1 at 𝑚𝜒 ∼ 6 GeV.