Introduction
Compton cameras are a promising tool in radiopharmaceutical therapy (RPT) treatment assessment and dosimetry, where gamma cameras perform sub-optimally due to the high energies of the emitted photons and low activities. The IRIS group is developing MACACO, a LaBr3-based Compton camera, for this application. The prototype MACACO III has been successfully used to visualize I-131...
Objective:
To evaluate the effect of a dermoprotective bra on the progression of acute radiodermatitis induced by radiotherapy, using as an objective biomarker a quantitative skin perfusion index obtained by Laser Doppler imaging.
Materials and methods:
Forty-seven patients with breast cancer treated with ultra-hypofractionated radiotherapy (total dose 26 Gy delivered in five fractions of 5.2...
Compton cameras (CCs) are promising imaging devices for nuclear medicine applications, as they can produce 3D images over a broad range of gamma-ray energies. Their flexible geometry suits compact and unconventional imaging setups. High energy resolution also improves background rejection and supports multi-isotope imaging, crucial in clinical contexts. Silicon detectors, due to their superior...
La terapia con protones es una forma de radioterapia más precisa, eficaz y segura que la radioterapia convencional en muchos casos de cáncer. Se trata de una técnica innovadora que está experimentando un notable crecimiento e interés. Actualmente, en España existen dos centros de protonterapia en funcionamiento, y está prevista la instalación de diez nuevos centros en distintas regiones del...
Boron Neutron Capture Therapy (BNCT) is an experimental form of radiotherapy that uses boron, injected to the patient within a target molecule that accumulates selectively in cancerous cells. This therapy exploits the large boron neutron capture cross-section to deliver a targeted dose from neutron irradiation. BNCT has shown great promise with the advent of accelerator-based technologies,...
Hadron therapy provides notable advantages compared to traditional radiotherapy, largely because it allows for precise dose delivery at the Bragg peak. The effectiveness of this approach could be further improved with the implementation of a near real-time ion-range verification system. Such monitoring would make it possible to minimize safety margins and better exploit the full potential of...
The PRIDE project (Proton Range and Imaging Device) aims to integrate a proton computed tomography (pCT) scanner and a proton range verification (pRV) detector into a single device for proton therapy. Our collaboration has carried out extensive work on pCT with experiments taking place in June and December 2022 at the Krakow CCB facility.
Proton range verification (pRV) consists of...
Metastatic bone cancer contributes to approximately 2 to 3 million cancer-related deaths worldwide annually. Between 5% and 10% of new cancer patients will develop bone metastases. A major challenge in treating this disease is the inability to perform imaging during particle radiation therapy (PRT), due to high radiation doses from frequent scans, patient pain, and mobility constraints....