Cardiac Positron Emission Tomography (PET) is a powerful molecular imaging technique, but its use is severely limited by poor spatial resolution. This limitation is particularly critical in preclinical studies with rodents, where small anatomical structures, high respiratory and heart rates exacerbate image blurring, partial volume effects, and quantitative errors [1]. These degradations arise...
Positron Emission Tomography (PET) relies on CT-based attenuation maps for accurate image reconstruction. The quality of these attenuation maps depends on CT acquisition parameters, particularly tube voltage and current. Higher tube currents improve image quality by reducing noise, but at the cost of higher radiation exposure. Conversely, reducing the current lowers the radiation dose but...
Total-Body Positron Emission Tomography (TB-PET) systems have become very popular in the recent times, due to their increased sensitivity with respect to Whole-Body (WB) PET systems. This is mainly attributed to their extended axial Field of View (FOV) and, in a few cases, the capability of Time of Flight (TOF) information. This combination enables the simultaneous visualization of the...
PET has consolidated as one of the most used and important molecular imaging techniques. However, there is still room for improvement. Specifically, boosting the system’s sensitivity will allow dose and/or time acquisition reduction without impacting the reconstructed image’s quality. BGO detectors have higher density when compared with the most used lutetium-based detectors, which translates...
Hybrid imaging systems integrating Positron Emission Tomography (PET), Magnetic Resonance Imaging (MRI), and Focused Ultrasound (FUS) are increasingly demanded in preclinical and translational research, yet no trimodal commercial solution currently exists. We have designed, assembled, and validated a dedicated PET insert based on monolithic LYSO crystals (33×25.4×8 mm³) with 67 mm of axial...
