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SUMMARY:Radionuclide therapy assessment with MACACO III+
DTSTART;VALUE=DATE-TIME:20241119T171800Z
DTEND;VALUE=DATE-TIME:20241119T172800Z
DTSTAMP;VALUE=DATE-TIME:20260421T175706Z
UID:indico-contribution-25505@indico.ific.uv.es
DESCRIPTION:Speakers: Gabriela Llosá (IFIC-CSIC)\nThe IRIS group at IFIC 
 (Valencia\, Spain) continues the development of Compton cameras and their 
 application to radionuclide therapy with successful results.\n\nThe previo
 us prototype\, MACACO III\, was composed of three detector planes. Each pl
 ane features one LaBr3 crystal of size 25.8 mm x 25.8 mm x 5 mm\, coupled 
 to a SiPM array. The system was initially tested with phantoms filled with
  FDG and I-131\, as well as thyroid cancer patients in collaboration with 
 La Fe Hospital (Valencia). Following these tests\, studies with alpha emit
 ters were also conducted. In addition to Monte Carlo detailed simulations 
 that indicated the potential for imaging Ac-225\, this isotope was also su
 ccessfully imaged experimentally in collaboration with the Léon Bérard h
 ospital in Lyon.\n\nHowever\, these measurements evinced the lack of effic
 iency of MACACO III which has prompted the use of larger detector planes. 
 MACACO III+ is a two-plane system in which the first plane is the same as 
 in MACACO III and the second plane is composed of four such detectors. Sim
 ulations show the benefits of this improvement in the reconstructed images
 . MACACO III+ has been tested experimentally with Derenzo-like phantoms an
 d also with mouse phantoms and live mice. Further tests are foreseen and a
 nother four-detector plane is under development.\n\nhttps://indico.ific.uv
 .es/event/7664/contributions/25505/
LOCATION:
URL:https://indico.ific.uv.es/event/7664/contributions/25505/
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