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SUMMARY:XEMIS: low dose 3 γ  medical imaging with a single-phase  liquid 
 xenon  Compton camera
DTSTART;VALUE=DATE-TIME:20170303T110000Z
DTEND;VALUE=DATE-TIME:20170303T120000Z
DTSTAMP;VALUE=DATE-TIME:20260429T095159Z
UID:indico-event-2915@indico.ific.uv.es
DESCRIPTION:\n    The XEMIS (XEnon Medical Imaging System) program develop
 ed at Subatech laboratory proposes a low dose functional medical imaging t
 echnique based on the detection in coincidence of 3γ rays. This innovativ
 e imaging modality aims to directly reconstruct the position of each disin
 tegration of  a specific (β+γ) radioisotope: the Sc-44\, using for the 
 first time a liquid xenon (LXe) camera. The benefit of this technique is e
 xpressed directly in a large reduction in the dose administered to the pat
 ient and/or the exam time. A preliminary R&D program has been successfully
  completed with a small dimensions LXe time projection chamber (TPC)\, cal
 led XEMIS1\, that holds 30 kg of xenon with a drift length of 12 cm. The r
 esults obtained from a detailed study of the detector response have provid
 ed the experimental evidence of the feasibility of the 3γ imaging techniq
 ue. Based on the good results obtained with XEMIS1\, a larger-scale protot
 ype for small animal imaging is now under construction. XEMIS2 is a single
 -phase cylindrical LXe TPC with 200 kg of xenon (active mass 70 kg) and a 
 total drift length of 24 cm. The particular geometry of XEMIS2 was specifi
 cally designed to provide a full coverage of the small animal\, allowing t
 he detection of the 3γ rays with a high sensitivity thanks to its large a
 xial field of view. Moreover\, since XEMIS2 has been designed for preclini
 cal applications in hospital centers\, a compact and completely safe cryog
 enic infrastructure called ReStoX (Recovery and Storage of Xenon) has been
  developed and successfully installed at Subatech. The XEMIS2 camera will 
 be operational and available from 2017 for preclinical research at the Cen
 ter for Applied Multimodal Imaging (CIMA) located in the Nantes Hospital.\
 n    In this talk\, I will give an overview of the XEMIS project. I will p
 resent and discuss the latest results obtained with XEMIS1 and in particul
 ar\, I will be focused in the ionization signal produced after the interac
 tion of an ionizing particle with the LXe. Further\, I will introduce the 
 new prototype XEMIS2 and I will show that the expected results are compati
 ble with the necessary requirements for small animal imaging with a liquid
  xenon Compton camera\, and very promising for the future of the 3γ imagi
 ng technique.\n     \n\nhttps://indico.ific.uv.es/event/2915/
LOCATION:IFIC Seminar Room\, 1.1.1
URL:https://indico.ific.uv.es/event/2915/
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